WebSep 28, 1999 · In an attempt to isolate new markers of the normal process of epidermal differentiation we previously have cloned a cDNA encoding a novel β-galactoside-binding protein (), galectin-7 (8, 9).Galectin-7 is the … WebApr 7, 2024 · As an important component of solid tumors, mast cells show specific phenotypes in various tumor microenvironments. However, the precise mechanism of mast cell accumulation and the phenotypic features of thyroid cancer (TC) remain largely unknown. Here, we found that mast cells were obviously recruit …
(PDF) Expression and Functions of Galectin-7 in Human
WebNov 18, 2024 · The galectin-7 knockdown results in reduced differentiation and increased proliferation of keratinocytes. Moreover, it was shown that galectin-7 positively regulates microRNA (miR)-203 expression, which in turn is used for regulating keratinocyte differen-tiation and proliferation. To determine how galectin-7 regulates keratinocyte proliferation WebGalectin-7 is a p53-induced protein and is abnormally expressed in variety of tumors such as melanoma, lung cancer and colon cancer. In UVB-induced sunburn keratinocytes, the expression of Galectin-7 is markedly increased due to the genotoxic stress-induced p53 activation. Both positive and negative regulatory roles of Galectin-7 have been ... brewtown tales john gurda
StockNews.com Begins Coverage on Galectin Therapeutics …
WebThe Galectin-7 gene is induced by tumor suppressor protein p53 transcriptional activity following genotoxic events. A pro-apoptotic protein, Galectin-7 functions intracellularly upstream of JNK activation and cytochrome-c release. This protein has been shown to increase the susceptibility of keratinocytes to UVB induced apoptosis, an essential ... Web52 minutes ago · Galectin Inhibitors Drugs Have Emerged As New Focused Domain For Cancer Clinical Researchers Says Kuick ResearchDelhi, April 14, 2024 (GLOBE … WebNov 30, 2016 · HER-2 positive tumors are among the most aggressive subtypes of breast cancer and are frequently associated with metastasis and poor outcome. As with other aggressive subtypes of breast cancer, these tumors are associated with abnormally high expression of galectin-7 (gal-7), which confers metastatic breast tumor cells with … brewtown trading cards