WebOct 21, 2009 · The metabolic syndrome (MetS) is one of the most important challenges to public health and biomedical research. Animal models of MetS, such as leptin-deficient … WebOct 1, 2024 · Chronic low-grade inflammation plays a pivotal role in the pathogenesis of obesity, due to its associated chronic diseases such as type II diabetes, cardiovascular diseases, pulmonary diseases and cancer. Thus, targeting inflammation is an attractive strategy to counter the burden of obesity-induced health problems. Recently, food-derived …
Mouse Models of Diabetes, Obesity and Related Kidney Disease
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Animal models of obesity - Speakman - Wiley Online Library
WebDescription. The Center for Advanced Preclinical Research (CAPR) specializes in evaluating the efficacy of preclinical compounds, existing drugs, or biologics (therapeutics) in genetically engineered mouse models, GEM-derived allograft (GDA) models, or patient-derived mouse xenografts (PDX).We partner primarily with Center for Cancer Research … WebPersonal Summary Zongjian Zhu, ... My research started in the areas of obesity, ... along with a variety of strategies in cancer prevention using animal mammary tumorigenic model and clinical ... WebThe focus of this overview is on the animal models of obesity most commonly utilized in research. The models include monogenic models in the leptin pathway, polygenic diet-dependent models, and, in particular for their historical perspective, surgical and chemical models of obesity. However, there are far too many models to consider all of them … disco microsoft teams