WebOct 1, 2016 · Paclitaxel is commonly used as first-line chemotherapy for advanced ovarian cancer and as adjuvant treatment, in combination with cisplatin or carboplatin, for residual disease. Taxanes (paclitaxel and docetaxel) are associated with numerous side effects, particularly including neurotoxic phenomena [ 1] . WebSep 29, 2024 · PURPOSE Limitations of the paclitaxel-doxorubicin-cisplatin (TAP) regimen in the treatment of endometrial cancer include tolerability and cumbersome scheduling. The Gynecologic Oncology Group studied carboplatin plus paclitaxel (TC) as a noninferior alternative to TAP. METHODS GOG0209 was a phase III, randomized, noninferiority, …
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WebDec 2, 2015 · Carboplatin + paclitaxel (also known as carbo-taxol) is given to shrink tumors and alleviate (lessen) symptoms of ovarian cancer. If the disease is not metastatic (spread outside the abdomen), carboplatin + paclitaxel is commonly given with the goal of cure. If the disease is metastatic, carboplatin + paclitaxel may not be curative, but may ... WebAim: To study the toxicity profile and response rates of weekly paclitaxel given as neoadjuvant chemotherapy (NACT) in patients with locally advanced breast cancer. … terrapin terpwin station
Carboplatin and Paclitaxel for Advanced Endometrial Cancer: …
WebJul 27, 2024 · Chemical name: Paclitaxel Class: Taxane chemotherapy. Abraxane and Taxotere are other taxanes. How it works: Taxanes interfere with the ability of cancer cells to divide. Uses: Taxol usually is given in combination with other chemotherapy medicines and is used after surgery to: reduce the risk of early-stage breast cancer coming back WebNanoparticle albumin-bound paclitaxel (nab-paclitaxel) is a solvent-free formulation of paclitaxel that avoids the risk of hypersensitivity reactions commonly observed with solvent-based taxanes (ie, paclitaxel and docetaxel) and the need of premedication. The dose of 260 mg/m 2 administered intravenously over 30 minutes every 3 weeks is ... WebNov 20, 2024 · Purpose: Limitations of the paclitaxel-doxorubicin-cisplatin (TAP) regimen in the treatment of endometrial cancer include tolerability and cumbersome scheduling. The Gynecologic Oncology Group studied carboplatin plus paclitaxel (TC) as a noninferior alternative to TAP. Methods: GOG0209 was a phase III, randomized, noninferiority, open … terrapin tile ithaca ny