Web3 Jan 2024 · The bacterial enzyme MenD, or 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) synthase, catalyzes an essential Stetter reaction in menaquinone (vitamin K2) biosynthesis via thiamine diphosphate (ThDP)-bound tetrahedral post-decarboxylation intermediates ... Macromolecules Web2-Sukcinil-5-enolpiruvil-6-hidroksi-3-cikloheksen-1-karboksilna-kiselina sintaza (EC 2.2.1.9, SEPHCHC sintaza, MenD) je enzim sa sistematskim imenom isochorismate:2-oksoglutarat 4-oksopentanoattransferaza (dekarboksilacija). Ovaj enzim katalizuje sledeću hemijsku reakciju. izohorizmat + 2-oksoglutarat 5-enolpiruvoil-6-hidroksi-2-sukcinil …
Catalytic mechanism of the SEPHCHC synthase (MenD) in …
Web10 Menaquinone as Well as Ubiquinone as a Crucial Component in the Escherichia coli Respiratory Chain Naoko Fujimoto 1, Tomoyuki Kosaka 2 and Mamoru Yamada 1,2 1Graduate School of Medicine, Yamaguchi University, Ube 2Faculty of Agriculture, Yama guchi University, Yamaguchi Japan 1. Introduction Web2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate … snacks of summer
Biosynthesis of Menaquinone in E. coli : Identification of an …
WebOther name(s): SEPHCHC synthase; MenD. Systematic name: isochorismate:2-oxoglutarate 4-oxopentanoatetransferase (decarboxylating) Comments: Requires Mg 2+ for maximal activity. This enzyme is involved in the biosynthesis of vitamin K 2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter ... Web9 Mar 2024 · Gene ID: 946720, updated on 9-Mar-2024. Summary. Mistakenly thought to be SHCHC synthase (Jiang, 2007). [More information is available at EcoGene: EG10579]. The menD gene product catalyzes the first committed step in the biosynthesis of menaquinone. Web3d structure of chain 5eja_c - ecmend-thdp-mn2+ complex soaked with 2-ketoglutarate for 2 min and soaked with isochorismate for 7 min - 5eja cansars rms shopfitting